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Magnetofection combines chemical and physical approaches. This involves combining nucleic acids, transfection reagents (polymers, lipids) or viruses with magnetic nanoparticles to improve transport of the material to the cell, directed by a specific magnetic field.
Specificities
:
• High viability of transfected neurons
• Effective from the 1st to the 21st day after dissection
• Transgene expression for up to 7 days
• Non-toxic and fully biodegradable
• Compatible with the use of serum
Applications :
• Suitable for all types of neuronal cells: primary neurons, neural cell lines, etc
• Suitable for all nucleic acids: DNA, oligonucleotides, mRNA, siRNA, shRNA