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Reagents for CRISPR-Cas9

PolyMag CRISPR

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• For genome editing using DNA or RNA
• Transfection reagent combined with magnetic nanoparticles to provide a high level of plasmid DNA and/or mRNA expressing Cas9 protein and guide RNA (gRNA)
• Based on patented Magnetofection technology: nanoparticles composed of a magnetic iron oxide core coated with cationic molecules
• Increased transfection efficiency
• Ideal for co-transfection of pDNA/pDNA*, pDNA/gRNA**, pDNA/mRNA
• Low cellular toxicity
• For use with magnetic plates

ViroMag CRISPR

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• Viral magnetic trasduction activator for CRISPR/Cas viruses (adenovirus, lentivirus, retrovirus, etc.)
• Based on patented Magnetofection technology: nanoparticles composed of a magnetic iron oxide core coated with cationic molecules
• Greatly increases the transduction efficiency of the CRISPR/Cas9 viral system
• Enables genome editing even in primary cells, which are difficult to transduce and non-permissive
• For use with magnetic plates

RmesFect CRISPR

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• Designed for mRNA/gRNA transfection
• Compatible with serum and all culture media
• Protects RNA from degradation

Pro-DeliverIN CRISPR

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• Transfection reagent for transmission of recombinant Cas9 protein or Cas9/gRNA RNP complexes
• Recombinant Cas9 protein transmitted more rapidly than nucleic acid and fully active once inside the cell. No latency period, unlike the transciption and translation machineries required for nucleic acids